Introduction. In the beginning of XXI century national economies of some countries were transformed through structural changes associated with the formation of the new postindustrial order. These changes require adequate theoretical understanding. The article discusses the structure of the total social product reproduction process with the participation of two entities: material and information sectors of the economy. Theoretical analysis. Simple and expanded reproduction of the total social product with the participation of the information sector are analyzed in the article. The puts forward the hypothesis about the existence of economic law of priority development of the information sector of the economy at the stage of postindustrial social system formation. The current state of Russian economy analysis revealed the existence of some negative trends: structural deformation and de-industrialization, occurring on the backdrop of protracted economic stagnation. Results. There made a conclusion about the necessity of elaboration of a comprehensive national strategy for the development of the information sector of economy, which will be able to become an engine of upgrade and diversification of Russian national economy structure and to overcome its raw materials dependence.