Introduction. Knowledge and the subjects whose activity results in increased knowledge play an important role in the modern economy, including information clusters. Theory. The “competitive region — competitive state” relationship is often considered in the design of clusters. Analysis. The information cluster, allowing for its specificity, should be macroeconomic, considered at the country level. Results. The structure of a competitive economy, developed by the author, allows one to consider macroeconomic clusters as a basis to ensure and improve the country’s competitiveness and to consider competitive business entities as a framework determining the competitiveness of the region and the country. In today’s Russian Federation, the formation of clusters goes quite active, with the support of governmental agencies; however, the number of clusters is not high enough, many spheres of activity and regions being clustered poorly. Conclusions. Russian information clusters should be formed to promote a knowledge economy and an increase of knowledge to design a framework for improving the competitiveness of businesses, regions, and the country in the whole.