Introduction. The population change is an actual direction of research not only for economists, but also for sociologists, political scientists, and psychologists. The author presents the author’s results of modeling the population of the Saratov region of working age. Theoretical analysis. For the economy of the Saratov region, it is necessary to analyze the use of labor resources in order to carry out literate policies. The population of the region shows a negative dynamics, which in general affects not only the number of labor resources, but also the regional macroeconomic indicators and the labor market. Empirical analysis. The policy of economic development of the Saratov region and Russia as a whole is aimed at changing the boundaries of the able-bodied population, in this connection, the article models variants with changing upper and lower boundaries of working age. The use of the results of this study shows how much such changes are needed, and to what extent, they are possible at the present time. Results. Calculations of the model showed that in the Saratov region a complex demographic situation that requires the development and implementation of appropriate measures aimed at preserving the working-age population. Change in the upper limits of working age adversely affects the economic development of the region.